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EU-OPENSCREEN: ISIDORe antibody discovery services

Call Submission Guidelines

Application Guidelines

General

Within the frame of ISIDORe (grant agreement No. 101046133), EU-OPENSCREEN ERIC collaborates with external partners (Fondazione per l'istituto di ricerca in biomedicina, IRB (CH), Institute of Biochemistry and Biophysics of the Polish Academy of Science, IBB-PAN (PL), Maria Sklodowska-Curie National Research Institute of Oncology, MSCNRIO (PL), Medical University of Warsaw, MUW (PL), and EC Joint Research Centre (JRC) Nanobiotechnology Laboratory (europa.eu) to offer support for the development of antibody therapeutics.

Open call information

New ISIDORe open calls for proposals are advertised on the project website: https://isidore-project.eu/calls/

‘How to apply’ and eligibility criteria can be found at https://isidore-project.eu/calls/#how-to-apply and  https://isidore-project.eu/calls/#eligibility, respectively.

For information and support during the application process please contact the ISIDORe team at contact@isidore-project.eu and/or the EU-OPENSCREEN team at scientificprojects@eu-openscreen.eu.

Application

Full applications are submitted to EU-OPENSCREEN ERIC and managed via ARIA (please login or register an aria account at https://apply.eu-openscreen.eu/)

Full applications can be submitted at https://apply.eu-openscreen.eu/submit-call/eu-openscreen-isidore-antibody-discovery-services.

Applicants commit to having obtained legal and ethical consent regarding their research, their samples and/ or their data prior to submitting their application.

Applicants must agree to comply with the access, IP and dissemination policies described in the statutes of EU-OPENSCREEN ERIC (available at https://www.euopenscreen.eu/fileadmin/user_upload/newsroom_and_downloads/201210_Statutes_V3_FINAL.pdf), if applicable.

Applicants must agree to comply with the EU-OPENSCREEN privacy policy and terms of submission (available at https://drive.eu-openscreen.eu/index.php?id=137).

Proposal review

The review process of applications consists of two evaluation steps (1. Technical; 2. Scientific). The application will remain strictly confidential throughout the review process. Reviewers will be bound by a non-disclosure agreement.

Two independent external experts will evaluate the scientific excellence of the proposal. Innovation potential and gender aspects of the project-specific research questions and methods will also be considered. The technical feasibility will be assessed by the ISIDORe technical  experts. Herein, technical reviewers will assess whether appropriate resources for the technical implementation of the projects are available at the sites.

Application form (via ARIA):

Complete the fields with details of the desired research:

*mandatory fields

Application Title:* please provide a title for your project.

Application Team: In addition to the applicant, indicate other members of your home institution that will be part of the application. Only scientists mentioned in this section will be eligible to manage or modify the application in the future. To add team member(s), they need to register an account in aria.

Indicate the call you are applying to:

Enter your ISIDORe pre-application ID number:

Abstract of the scientific background, and main objectives:* please provide a concise project overview (max 3000 characters).

Relevant publications:* please report the relevant literature (up to 5 publications).

Please provide any patent or conflict of interest related to this project. If necessary, any relevant information can be provided as additional attachment.    

Attachments: In case of patent(s), please upload attachments here.

Please provide a brief description of yours/ PI’s CV:* please include in this section a brief overview of your education, professional background, and expertise that supports the proposed research. (max 3000 characters)

Description of scientific work including a detailed description of your previous and current work relating to the proposed project and planned follow-up experiments:* (max 5000 characters). Please include type (size, scale, materials) and number of specimens, and where relevant, indicative drawings. Depending on the type of tests, number of tests to be carried out and their sequence, the type and level of excitation, input quantities or needed characterisation, the (output) response quantities to be measured and the required instrumentation.

Please select the support needed to carry out your project:* (multiple options are possible):

assay development, nanobody library preparation, antigen or antibody identification, nanobody identification, antigen or antibody design and engineering nanobody design and engineering, antigen and/or antibody production and purification, antigen and/or antibody characterization, recombinant production of proteins, 3D structural models, physico-chemical measurements of quality attributes, assessment of endotoxin contamination, phenotypic antiviral screening, binding assay, validation, other (please specify)

Please indicate biosafety level for the biological material if known/any. (max 200 characters)

Indicate your contribution to the proposed project.* Indicate how you will contribute to the proposed research in terms of resources, expertise, materials, instrumentation, specimen, reagents etc (max. 1000 characters).

Attachments: please upload relevant attachment(s) to support your proposed research if available

Status/ proof of methodology.* Please present data that validates your scientific approach.  If available, please include data that compares your results against available standards. Please comment on the maturity of your proposed research (max 3000 characters).

What are your IP rights regarding your proposed system, which know-how do you own versus license?*

Are there any known technical challenges related to the implementation of the project?* If yes, please comment (max. 3000 characters)

Please indicate the expectation on the outcome of the proposed project.* Please indicate milestone(s)/ end-goals of the proposed research with approx. expected timelines (max 1000 characters).

Please comment on the innovative potential of proposed research.* The proposal should demonstrate the originality and innovation of the proposed work with the state-of-the-art and the impact the expected results will have on current and future research or practice (max. 3000 characters).

Training (involvement of young scientists):* indicate participation of young researchers (PhD, post-docs) as users in the project (max 1000 characters)

Please describe gender aspects of the proposed research.* Please consider gender balance in your team and integrate the gender dimension in the content of research (max 3000 characters).

Additional attachments: please upload any additional document relevant for the evaluation of this proposal.

Ethics: does the activity proposed within this call involve research using human cells or tissues (other than from Human Embryos/Foetuses), research on animals or any other issues that should be taken in consideration?*

☐ Yes (if yes, please specify) ☐ No

Comments: please add any additional relevant comment and/or information. (max. 1000 characters)

User statement:

I confirm to be the principal researcher of the submitted project as it is described in the present application*.

I confirm that all relevant authorizations, declarations and accreditation from competent authorities have been obtained in order to process the above-mentioned samples and data through EU-OPENSCREEN, for the requested purposes, in full compliance with the applicable EU and National laws.*

All publications resulting or including data obtained through EU-OPENSCREEN will be published under Open Access.*

Legal requirements for exporting/importing materials to/from other countries have been met.*

Do you agree that EU-OPENSCREEN and ISIDORe partners may use general information about your project for outreach and reporting purposes (respecting confidentiality of project specifics)? in case that you do not agree, please give your explanation in the comment section below.

Yes No (please specify)

 

 

Call Closes:
30-May-2024 23:00 CEST

Click the button to begin your application for this call. Your draft applications will also appear here as well as on your dashboard and can be continued at any point.

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